GPAT Syllabus 2025 - Downlaod GPAT Syllabus PDF, Topic-wise Weightage

Subjects

Topics

Pharmacology

General Pharmacology

Principles of toxicology

Drugs acting on urinary system

Pharmacology of peripheral nervous system

Pharmacology of central nervous System

Pharmacology of cardiovascular system

Immunopharmacology

Drugs acting on Respiratory system

Pharmacology of Endocrine system

Neurohumoral transmission in autonomic and central nervous system

Vitamins & Minerals

Chemotherapy

Autacoids and their Antagonists

Pharmacology of drug acting on the gastrointestinal tract

Chronopharmacology

Physical Chemistry

Composition & physical states of matter

Refractive index

Solutions

Electrochemistry,

Kinetics

Colligative Properties

Thermodynamics

Ionic equilibrium

Physical Pharmacy

Buffer

Solubility

Matter, properties of matter

Viscosity and rheology

Surface and interfacial phenomenon

Dispersion systems

Complexation

Micromeritics and powder rheology

Organic Chemistry

General principles

Pericyclic reactions

Aromaticity & chemistry of aromatic compounds

Different classes of compounds

Amino acids & proteins

Different aromatic classes of compounds

Polycyclic aromatic hydrocarbons

Stereochemistry

Carbohydrates

Carbonyl Chemistry

Heterocyclic Chemistry

Protection & deprotection of groups

Bridged rings

Kinetic & thermodynamic control

Dispensing and Hospital Pharmacy

Introduction to laboratory equipment, weighing methodology, handling of prescriptions, labelling instructions for dispensed products

Posological calculations involved in the calculation of dosage for infants.

Study of current patent and proprietary products, generic products and selected brand products, indications, contraindications, adverse drug reactions, available dosage forms and packing

Compounding and dispensing of following prescriptions

Reading and counselling of prescriptions from the clinical practice

Enlarging and reducing formula, displacement value

Preparations of formulations involving allegation, alcohol dilution, isotonic solution

Pharmaceutical Chemistry

Pharmaceutical Inorganic Chemistry

Dentifrices, desensitizing agents, & anticaries agents

Pharmaceutical Impurities

Isotopes

Monographs

Medicinal Chemistry

Various classes of therapeutic agents

Different classes of therapeutic drugs

Therapeutic classes of drugs

Different classes of therapeutic drugs

Pharmaceutical Jurisprudence

Narcotic Drugs and Psychotropic Substances Act, and Rules thereunder

Factory Act

Shops and Establishment Act

Introduction to Intellectual Property Rights and Indian Patent Act 1970

An Introduction to Standard Institutions and Regulatory Authorities such as BIS, ASTM, ISO, TGA, USFDA, MHRA, ICH, WHO

Minimum Wages Act 1948

Prevention of Food Adulteration Act 1954 and Rules

Industrial Development and Regulation act 1951

Drugs and Magic Remedies (Objectionable Advertisements) Act 1954

Medicinal and Toilet Preparations (Excise Duties) Act 1955, Rules 1976

Historical background Drug legislation in India, Code of Ethics for Pharmacists

The Pharmacy Act 1948

Drugs and Cosmetics Act 1940, Rules 1945, including New Drug applications

Consumer Protection Act

Indian Pharmaceutical Industry- An Overview

Medical Termination of Pregnancy Act 1970 and Rules 1975

Prevention of Cruelty to Animals Act 1960

Drug (Price Control) Order

Pharmaceutical Management

Introduction to management

Inventory Management

Communication

Research Management

Human resource and development (HRD)

Planning and Forecasting

Organization

World trade organization (WTO) and trade-related intellectual property rights (TRIPS)

Standard institutions and regulatory authorities

GATT

Marketing Research

Leadership and motivation

Pharmaceutics

Pharmacy Profession & Introduction to Pharmaceuticals

Introduction to dosage form

Biological products

Pharmaceutical Plant, location, layout

Ophthalmic preparations

Pre formulation

Packaging Materials

Cosmetics

Pilot plant scale-up techniques

Dosage Form Necessities and Additives

Powders

Sources of drug information

Tablets

Parenteral - product requiring sterile packaging

Suspensions

Emulsions

Suppositories

Stability of formulated products

Prolonged Action Pharmaceuticals

Novel Drug delivery system

GMP and Validation

Semisolids

Allopathic dosage form

Crude extract

Allergenic extract

Capsules

Liquids(solutions, syrups, elixirs, spirits, aromatic water, liquid for external uses)

Pharmaceutical Aerosols

Pharmaceutical Engineering

Material of constructions

Drying

Size reduction and size separation

Extraction

Mixing

Crystallization

Automated process control systems

Industrial hazards & safety precautions

Evaporation

Distillation

Fluid flow

Heat transfer

Filtration and Centrifugation

Dehumidification and humidity control

Refrigeration and air conditioning

Pharmacognosy

Introductory Pharmacognosy

Classification of crude drugs

Plant products

Principles of plant classification

Pharmaceutical aids

Animal products

Traditional herbal drugs

Plants based industries and research institutes in India

Patents

Ayurvedic system of medicine

Homeopathic system of medicine

Toxic drugs

Enzymes

Natural pesticides and insecticides

Adulteration and evaluation of crude drugs

Quantitative microscopy

Factors influencing quality of crude drugs

Techniques in microscopy

Introduction to phytoconstituents

Biogenetic pathways

Carbohydrates & lipids

Tannins

Volatile oils

Resinous drugs

Glycosides

Alkaloids

Extraction and Isolation Techniques

Phytopharmaceuticals

Quality control and Standardization of herbal drugs

Herbal formulations

Worldwide trade of crude drugs and volatile oils

Herbal cosmetics

Human Anatomy and Physiology

Cell physiology

Endocrine Glands

Reproductive System

Gastrointestinal tract

Respiratory System

Autonomic nervous system

Cardiovascular system

Lymphatic system

The Blood

Sense organs

Skeletal System

Central Nervous system

Urinary System

Pharmaceutical Analysis

Importance of quality control in pharmacy

Acid-base titrations

Gravimetry

Extraction techniques

Potentiometry

Calibration

General principles of spectroscopy

Mass spectrometry

Polarography

Nephelometry & Turbidimetry

Ultraviolet-visible Spectrometry

Spectrofluorimetry

Flame photometry & atomic absorption spectrometry

Infrared spectrometry

Miscellaneous methods of analysis

Non-aqueous titrations

Oxidation-reduction titrations

Precipitation titrations

Complexometric titrations

Proton nuclear magnetic resonance spectrometry

Chromatography

Miscellaneous

Clinical Pharmacy and Therapeutics

Drug information services, Drug interactions

Drug interaction in pediatric and geriatric patients, drug treatment during pregnancy, lactation and menstruation

Therapeutic drug monitoring, adverse drug reaction (ADR), types of ADR, Mechanism of ADR. Drug interaction, Monitoring and reporting of ADR and its significance

Age-related drug therapy: concept of posology, drug therapy for neonates, paediatrics and geriatrics. Drugs used in pregnancy and lactation

Drug therapy in gastrointestinal, hepatic, renal, cardiovascular and Respiratory Disorders

Pharmacovigilance, Therapeutic drug monitoring, Neutraceuticals, essential drugs and rational drug usage

General Principles, preparation, maintenance, analysis of observational records in Clinical Pharmacy

Drug therapy in infections of respiratory system, urinary system, infective meningitis, TB, HIV, malaria and filaria

Drug therapy for thyroid and parathyroid disorders, diabetes mellitus, menstrual cycle disorders, menopause and male sexual dysfunction

Drug therapy for malignant disorders like leukaemia, lymphoma and solid tumours

Drug therapy for rheumatic, eye and skin disorders

Clinical trials, type and phases of clinical trials, placebo, ethical and regulatory issues including Good clinical practice in clinical trials

Drug therapy for neurological and psychological disorders

Biochemistry

Cell

Lipids

Enzymes

Nucleic acids

Vitamins

Biological oxidations & reductions

Carbohydrates

Proteins

Hereditary diseases

Biopharmaceutics and Pharmacokinetics

Bio-pharmaceutics

Bio-pharmaceutical statistics

Bio-availability & Bio-equivalence

Biotechnology

Plant Cell and Tissue Culture

Fermentation Technology and Industrial Microbiology

Recombinant DNA Technology

Process and Applications

Animal Cell Culture

Biotechnology-Derived Products

Pathophysiology

Basic principles of cell injury and adaptation

Neoplastic diseases

Pathophysiology of common diseases

Laboratory tests for Liver function tests and kidney function tests

Immunopathology including amyloidosis

Infectious diseases

Basic mechanisms of inflammation and repair

Disorders of fluid, electrolyte and acid-base balance

Disorders of homeostasis: white blood cells, lymphoid tissues, and red blood cells related diseases

Microbiology

Introduction to Microbiology

Microscopy and staining technique

Biology of Microorganisms

Microbial spoilage

Vaccines & Sera

Fungi and Viruses

Aseptic Technique

Sterilization & Disinfection

Microbial Assay

Particulars

Details

Mode of the exam

Online

Exam duration

3 hours

Total number of questions

125

Maximum marks

500

Type of questions

Multiple Choice Questions (MCQs)

Marks per question

4 marks for each question

Negative marking

+4 for every correct response

-1 for every incorrect response